Imagine waking up every day full of energy, ready to face the day's challenges with a clear mind and a strong body. For many, this is more of a dream than reality. But what if there was a way to approach this state? Let's explore what nicotinamide mononucleotide (NMN) is and how it can be the key to improving your quality of life.

What happens when you take nicotinamide mononucleotide supplements?

• First hour: NMN enters the cells and starts NAD+ biosynthesis. NMN (Nicotinamide mononucleotide) is quickly absorbed into the blood and transported to tissues where it is used for NAD+ biosynthesis.
  
  
• 5 hours: NAD+ levels begin to rise in the blood. Increased levels of NAD+ metabolites in blood plasma indicate increased use of NAD+ in cells and tissues.
  
  
• 3 days: Promotes mitochondrial health and cellular energy production. Improves mitochondrial replication and supports the cells' powerhouse in the production of energy.
  
  
• 30 days: NAD+ levels increase by 40%. Clinical studies show a 40% increase in NAD+ levels in the blood after 30 days of NMN supplementation.
  
  
• 6 weeks: Improves muscle strength and performance. Partial improvement in muscle strength and performance in older men after 6 weeks of daily NMN supplementation.
  
  
• 8 weeks: Reduces markers of skin aging. Reduction of advanced glycation end products (AGEs), which are markers of skin aging.
  
  
• 10 weeks: Supports healthy insulin sensitivity. Increased use of NAD+ in skeletal muscle and improved insulin sensitivity.
  
  
• 3 months: Increases walking speed. Improvement in walking speed in elderly men after 3 months of daily NMN supplementation.
  
  
• 6 months: Maintains elevated NAD+ levels, supports overall health and healthy aging. Long-term maintenance of elevated NAD+ levels supports overall health and well-being.
  
  
• 1 year: Long-term benefits for aging. By using NMN supplements continuously for a year, you help maintain higher levels of NAD+, which supports healthy aging and potentially improves quality of life over time. Your natural decline in NAD+ is not only counteracted, but your body is also optimized for a healthier aging process. Cells, organs and body systems are now functioning at their best.

What is quality of life?

Quality of life is a broad term that includes both physical, psychological and social well-being. It is about how we experience our everyday life, our satisfaction with existence and our ability to live a satisfying life. For many, quality of life is also about living longer and healthier, which often leads them to explore various health and lifestyle interventions.

In today's society, we are increasingly concerned with finding ways to improve our health, both to increase our lifespan and to improve the quality of our years of life.

Imagine having enough energy to exercise regularly, enjoy a walk in nature or have the clarity to complete a demanding job. In today's society, we are increasingly concerned with finding ways to improve our health, both to increase our lifespan and to improve the quality of our years of life.

Personal stories

To illustrate the importance of quality of life, let's take a look at some personal stories. Monia, a 75-year-old pensioner, found a new life after starting NMN.

"I am retired and was thrilled with this product. Have now been using NMN (Nicotinamide Mononucleotide) for 1 month. After about a week my sleep was deeper and better. Had a lot of trouble sleeping before. I definitely have better energy, I can take on projects I couldn't take on before as I have been struggling with some ME.My days have become much clearer and I have better concentration.It also seems to speed up the healing wounds."

Why is nicotinamide mononucleotide important?

Nicotinamide mononucleotide (NMN) has received much attention in recent years for its potential health benefits. As a precursor to NAD+, an essential coenzyme in the body, NMN can play an important role in maintaining energy levels, supporting cognitive function and promoting overall health. Dr. David Sinclair, a distinguished researcher in aging research at Harvard, has been one of the most vocal proponents of NMN, and has shared his own positive experiences with the supplement.

In this article, we'll dive deeper into how NMN supplementation can improve your quality of life, focusing on the scientific findings, potential benefits, and practical advice for incorporating NMN into your daily routine.

NMN and Energy production

When we talk about energy, we often think of mental clarity and physical stamina. NMN (Nicotinamide mononucleotide) can contribute to both. Studies have shown that NMN can increase levels of NAD+, which in turn helps the mitochondria – the powerhouse of the cells – to produce energy more efficiently. Imagine being able to last a whole day without the usual afternoon slump. This can result in increased energy throughout the day, better stamina and a general feeling of well-being.

Read more about NMN 500mg capsules

Scientific explanation

To understand how NMN (Nicotinamide mononucleotide) works, we need to look more closely at the biochemistry. Mitochondria are known as the power plants of cells, and they produce ATP (adenosine triphosphate), which is the primary source of energy for our cells. NMN increases the levels of NAD+, which is essential for efficient ATP production.

What is nicotinamide mononucleotide (NMN)?

Definition and basic science

Foods containing nicotinamide mononucleotide (NMN) include broccoli, cabbage, cucumber and avocado, although the proportion is very low compared to supplements. (100 grams of broccoli and cabbage contain around 0.25-1.12 mg NMN)
NMN is a naturally occurring nucleotide derived from niacin (vitamin B3) and acts as a direct precursor to NAD+, which is essential for energy production and cellular function. Although these foods contain NMN, the concentrations are often not high enough to provide significant health benefits.

How NMN works in the body

When we consume NMN (Nicotinamide mononucleotide), it is quickly converted into NAD+ in the body. NAD+ is involved in many important processes, including energy production in the mitochondria, DNA repair and regulation of gene expression through sirtuins. These processes are essential for maintaining optimal cell health and preventing aging.

When NAD+ levels decline with age, this can lead to energy deficiency, increased oxidative stress and the accumulation of damaged DNA. By increasing NAD+ levels through NMN supplementation, we can potentially counteract these aging processes and promote better health and longer life.

Read more about NAD+  

The story behind research on nicotinamide mononucleotide

Research into NAD+ and NMN (Nicotinamide mononucleotide) began decades ago, but it is only recently that technological advances have made it possible to understand the full effect of these molecules. Many studies have been conducted on animals, and some are beginning to appear in humans, showing promising results.

The pioneers in research

One of the leading researchers in the field is Dr. Charles Brenner, who discovered the biochemical pathway that NMN follows to be converted to NAD+. His research has paved the way for many of the studies that now show the potential benefits of nicotinamide mononucleotide.

10 The benefits of NMN for quality of life

1. Improved cognitive function

How NMN affects the brain

Research has shown that NMN (Nicotinamide mononucleotide) can protect neurons and support cognitive function. This is partly due to increased levels of NAD+, which helps to maintain mitochondrial function and reduce oxidative stress in the brain. NMN can help improve memory, learning and general mental clarity.

Clinical studies and findings

Several studies have investigated the effect of NMN on cognitive functions. A study in mice showed that NMN (nicotinamide mononucleotide) supplementation improved memory and learning. Early human studies also show positive results, but more research is needed to confirm these findings in humans. However, these studies offer hope that NMN may be a valuable tool for maintaining cognitive health with age.

2. Increased physical performance

NMN and muscle health

With age, muscle mass and strength decrease, which can affect the quality of life. NMN (nicotinamide mononucleotide) can help by improving muscle energy metabolism, reducing inflammation and promoting muscle repair. This can help to maintain physical activity and functionality throughout life.

Examples of improved physical performance

Studies have shown that animals given NMN have increased endurance and muscle strength. Although human studies are underway, initial results show promising potential for similar effects. Many users also report increased energy and reduced fatigue, which can contribute to a more active and satisfying lifestyle.

3. Better metabolic health

Prevention of metabolic diseases

Metabolic health is a key factor in overall health. NMN (Nicotinamide mononucleotide) can help improve insulin sensitivity, regulate blood sugar levels and reduce the risk of metabolic syndromes such as diabetes and obesity. This can be particularly important for maintaining a healthy body weight and preventing chronic diseases.

NMN and weight loss

Several studies have indicated that NMN can help with weight loss by increasing metabolism and reducing fat storage. This can be especially helpful for those struggling with obesity and related health issues. By improving the body's ability to use energy efficiently, NMN can contribute to a healthier body weight and better metabolic health.

4. Anti-aging effects

Cell aging and NAD+

Aging is a complex process involving many biological mechanisms. NMN (nicotinamide mononucleotide) can help reduce the signs of aging by increasing NAD+ levels, which are essential for DNA repair and cellular health. This can help prevent cell damage and maintain the body's functions over a longer period of time.

Research and results

Animal studies have shown that NMN (Nicotinamide mononucleotide) can extend lifespan and improve quality of life. Although human studies are still ongoing, initial results give hope for similar effects in humans. This may mean that NMN may be a key to extending not only lifespan, but also quality of life.

5. Improved sleep quality

The role of sleep in health

Good sleep is essential for health and well-being. Sleep affects everything from cognitive function to physical health and emotional well-being. NMN can help regulate sleep cycles by improving energy metabolism and reducing stress. This can result in better sleep quality and a more rested feeling in the morning.

Personal experiences and studies

Many people who take NMN report improved sleep quality and less sleep problems. Although this is anecdotal evidence, it is supported by early studies showing similar effects. Better sleep can have a significant impact on the quality of life, as it affects both physical and mental health.

6. Improved eye health

How NMN affects vision

NAD+ plays an important role in maintaining the health of eye cells, especially the photoreceptor cells responsible for vision. With age, the levels of NAD+ in the eyes can decrease, which can contribute to the development of age-related eye diseases such as macular degeneration and glaucoma.

Studies and findings

A study on mice showed that NMN supplementation (Nicotinamide mononucleotide) could improve the structure and function of the retina. This included better vision and reduced loss of photoreceptor cells. This suggests that NMN may be useful in maintaining eye health and reducing the risk of eye diseases

7. Strengthened immune system

How NMN affects the immune system

The immune system often weakens with age, which makes us more susceptible to infections and diseases. NAD+ is important for the function of the immune system, and increasing levels through NMN (Nicotinamide mononucleotide) can help strengthen the body's defense mechanisms.

8. Improved heart health

How NMN supports heart function

The heart is one of the most important organs in the body, and its function can be affected by ageing. NMN (Nicotinamide mononucleotide) can help improve heart health by increasing energy production in heart cells and reducing inflammation. This can help maintain a healthy heart rhythm and reduce the risk of heart disease.

Research and results

Animal studies have shown that NMN can improve heart function and reduce damage to heart tissue. Early studies on humans also show promising results, and many hope that NMN can become an important part of treatments for heart disease in the future.

9. Increased stress resistance

How NMN reduces stress

Stress is a normal part of life, but chronic stress can have serious health consequences. NMN can help reduce stress by supporting energy metabolism and improving the body's ability to deal with stressors. This can result in a better overall sense of well-being and mental balance.

Clinical studies and findings

Research has shown that NMN (Nicotinamide mononucleotide) can reduce stress levels and improve mood in both animals and humans. One study found that NMN users reported less stress and a better ability to deal with daily challenges.

10. Improved skin health

How NMN can renew the skin

The skin is the body's largest organ, and its health can be affected by ageing, environmental factors and lifestyle. NMN (Nicotinamide mononucleotide) can help improve skin health by supporting cellular renewal and protecting against damage from free radicals. This can result in more youthful and radiant skin.

User experiences and results

Many people who take NMN report improved skin texture and fewer signs of aging. Combined with a healthy skincare routine, NMN can be a powerful ally in the fight against signs of skin ageing.

The science behind NMN

How NMN works

To understand how NMN works, it is important to delve into the science. NMN is a precursor molecule to NAD+, and NAD+ is involved in hundreds of enzyme reactions in the body, including energy production, DNA repair and cellular aging. When NAD+ levels drop, it can lead to energy depletion, accumulation of damaged DNA and ultimately cell death.

Scientific studies

By supplementing with NMN, we can increase NAD+ levels and thus support these important processes. Studies have shown that NMN can improve energy metabolism, protect against DNA damage and support healthy cell function. This can help improve our overall health and well-being.

How to take NMN

Dosage and use

It is important to follow the correct dosage recommendations for NMN. Most studies have used doses between 250-1000 mg per day, depending on the individual's needs, health profile and age. Some experts recommend starting with a lower dose and increasing gradually to find the most effective dose for each individual.

Several renowned researchers, including Andrew Huberman, a leading neuroscientist, and David Sinclair, a pioneer in aging research, use both NMN and NR. Huberman has confirmed in his podcast that he uses 1-2 grams of NMN and 500 mg of NR daily. While David Sinclair has stated that he uses 1 gram of NMN daily.

Best time for intake

For the best possible absorption, it is recommended to take NMN on an empty stomach. Some people prefer to take it in the morning to benefit from the energy boost throughout the day. Others may find it useful to take NMN before physical activity to improve performance.

Possible nicotinamide mononucleotide side effects

Nicotinamide mononucleotide (NMN) is generally considered safe; However, some individuals may experience mild side effects, such as nausea, headache or digestive problems. If you experience serious side effects, it is recommended to stop using and consult a healthcare professional.

Live Longer products

Introduction to living longer

At livelonger.no, our goal is to inspire a healthier and more balanced life. We are passionate about sharing knowledge, resources and advice to help you make informed choices for your health and well-being. Whether it concerns diet, exercise or mental health, we want to be your reliable source of information and motivation. Our vision is a world where everyone has the opportunity to live a long, happy and healthy life.

NMN grant

Live Longer offers several products with 99.9% proven pure NMN, designed to increase NAD+ levels and support overall health. These products include both capsules and nicotinamide mononucleotide powder, so you can choose the form that best suits your needs and lifestyle.

Check out our NMN 500mg capsules and our nicotinamide mononucleotide powder NMN - 100g

TMG grant

TMG (Trimethylglycine/Betain) contributes to a longer and healthier life by supporting several important body functions, such as methylation, improved liver function and increased energy and endurance.

Other products

• Test kit - Biological age
• Vitality Boost Bundle: NMN 100g + biological age test

How Live Longer can improve your quality of life

By incorporating Live Longer's products into your daily diet, you can take advantage of the many health benefits they offer. Our products are formulated to support energy levels, cognitive function, muscle strength and general well-being, which can contribute to a higher quality of life and a more active and fulfilling life.

Conclusion

NMN (Nicotinamide mononucleotide) represents a promising approach to improving quality of life by supporting energy production, cognitive function, physical performance and metabolic health. Although more research is needed to fully understand the full benefits of nicotinamide mononucleotide, preliminary results are very encouraging.

Living longer and healthier is no longer a distant dream. With NMN you can take the first steps towards a future full of vitality and well-being.

In this article, we have explored how NMN can improve the quality of life by supporting various aspects of our health. By understanding the science behind NMN and its potential benefits, you can make informed decisions about your health and well-being. Hope this information gives you insight and inspiration to explore NMN further and perhaps include it in your daily routine.

Frequently asked questions

What is nicotinamide mononucleotide?

Nicotinamide mononucleotide (NMN) is a nucleotide derived from vitamin B3 (niacin). It plays an important role in cellular metabolism and energy production. NMN helps produce nicotinamide adenine dinucleotide (NAD+), which is an essential cofactor in metabolic processes such as mitochondrial respiration and DNA repair.

What should you look for when buying NMN supplements?

When considering purchasing nicotinamide mononucleotide (NMN) supplements, it is essential to focus on the product's quality and safety. Many suppliers offer NMN without being able to document the product's purity through third-party testing, and some only test for the presence of impurities, not the purity of the NMN itself. To ensure you are getting a high quality product, you should choose NMN supplements that have been thoroughly tested by independent laboratories for both impurities and purity. Third-party test certificates give you peace of mind that the supplement contains exactly what is stated and that it is safe to use. Choose suppliers who are transparent about their testing procedures and who offer detailed information about their product's quality. This ensures that you are investing in an NMN supplement that truly supports your health and well-being.

What do nicotinamide mononucleotide supplements do?

Nicotinamide mononucleotide has several potential health benefits based on preliminary research: It may help increase NAD+ levels in the body which supports cellular energy production and ATP synthesis. This can promote overall health, support metabolic function and help slow the signs of aging. NMN can also reduce oxidative stress and inflammation while potentially improving DNA repair in cells. More research is still needed to confirm all possible benefits.

What is nicotinamide mononucleotide used for?

While research is still ongoing, nicotinamide mononucleotide supplements may provide benefits for age-related conditions. Some potential uses for NMN supplementation include helping with energy levels, metabolism, reduction of oxidative stress, antiaging effects, DNA protection, and support for brain and neurological health. NMN is being studied for its role in increasing NAD+ levels to support cellular health and fight aging processes in the body.

References.:

1. Ingestion of nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study. This study shows how the long-term effects of NMN can improve walking speed and sleep quality in older adults. PubMed
   
   
2. Ratiometric NAD+ Sensors Reveal Subcellular NAD+ Modulators. Mapping NAD+ dynamics in living cells and humans. American Chemical Society
   
   
3. Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice: comparison with exercise. This study shows that NMN supplementation increases metabolism and reduces obesity in mice. Nature.com
   
   
4. Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice . This study investigates the long-term effects of NMN on aging processes in mice, with positive results for energy production and cognitive function. PubMed
   
   
5. Nicotinamide mononucleotide supplementation ameliorates the impact of maternal obesity in mice. The research shows how NMN can improve metabolic health and physical performance. PubMed
   
   
6. NAD+ intermediates: The biology and therapeutic potential of NMN and NR. This article explores the biochemical mechanisms and potential therapeutic benefits of NMN. PubMed
   
   
7. NAD+ as the link between oxidative stress, inflammation, calorie restriction, exercise, DNA repair, longevity, and health span. The article highlights NMN's role in improving overall health and reducing oxidative stress. PubMed